CartiMax®

CartiMax^® is viable, cartilage fibers combined with cartilage allograft matrix to make a biologically-active scaffold with putty-like handling characteristics used to treat focal cartilage defects.  This product offers the potential to facilitate cartilage healing and regeneration along with ease of use.

Viable Chondrocytes
Characterization testing of CartiMax verifies the presence of functioning viable chondrocytes & chondrogenic growth factors.¹ Multiple studies have demonstrated that chondrocytes migrate and proliferate from the cartilage fibers and secrete components found in hyaline cartilage.^2,3,4

Optimal Handling Properties
Unlike other solutions that may require templates, trimming, gluing, suturing or other fixation methods, CartiMax has putty-like handling properties and easily conforms to defects of different shapes and sizes.

12 Month Shelf-Life
A ready-to-go, off-the-shelf solution that demonstrates stable viability up to twelve months post-cryopreservation.¹

High Volume of Material
While you may need multiple packages of another scaffold to fill a 2.5cm² lesion, one package of CartiMax contains enough cartilage matrix to fill up to a 5cm² lesion. Other products may require multiple packages to fill the same volume.

Reference:
¹Data on File, MTF Biologics.

²Albrecht F, Roessner A, Zimmermann E. Closure of osteochondral lesions using chondral fragments and brin adhesive. Archives of orthopaedic and traumatic surgery Archiv fur orthopadische und Unfall-Chirurgie. 1983;101:213–7. [PubMed].

³Lu Y, Dhanaraj S, Wang Z, et al. Minced cartilage without cell culture serves as an effective intraoperative cell source for cartilage repair. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2006;24:1261–70. [PubMed].

⁴Frisbie DD, Lu Y, Kawcak CE, DiCarlo EF, Binette F, McIlwraith CW. In vivo evaluation of autologous cartilage fragment-loaded scaffolds implanted into equine articular defects and compared with autologous chondrocyte implantation. The American journal of sports medicine. 2009;37(Suppl 1):71S–80S.